ABSTRACT
A 58-year-old man with Darier's disease developed endophthalmitis 3 days following left-sided cataract extraction with intraocular lens implantation. Vitreous cultures were positive for Pseudomonas aeruginosa, similar to previously cultured hyperkeratotic plaques on the patient. Despite emergent vitrectomy and aggressive treatment with systemic, intravitreal, and topical fortified antibiotics, the patient required evisceration 19 days postoperatively. Bacterial overgrowth within hyperkeratotic plaques may increase the risk of endophthalmitis following intraocular surgery in patients with Darier's disease.
AUTHORS
From Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio.
Originally submitted June 25, 2009. Accepted for publication February 25, 2010. Posted online June 30, 2010.
Supported in part by Research to Prevent Blindness, Inc., New York, New York.
The authors have no financial or proprietary interest in the materials presented herein.
Address correspondence to Julian D. Perry, MD, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, i-32, Cleveland, OH 44195.
doi: 10.3928/15428877-20100625-05
